An elderly patient admitted into the E.R. for a heart condition sees a familiar face, a long lost love who happens to be in the E.R. as well for a fractured arm, and the staff find themselves caught up in their love story. Meanwhile, Karev treats a troubled teenage patient (guest star Demi Lovato) whose parents brought her in for schizophrenia, and Meredith can't help but tell Cristina about her suspicions of Owen -- which inevitably messes with Cristina's head.
Elenco: Ellen Pompeo , James Pickens Jr. , Chandra Wilson , Justin Chambers , Kevin McKidd , Jesse Williams , Patrick Dempsey , Sara Ramirez , Sandra Oh , Jessica Capshaw , Sarah Drew , Camilla Luddington , Caterina Scorsone , Giacomo Gianniotti , Kelly McCreary , Katherine Heigl , Chyler Leigh , Eric Dane , Kim Raver , T.R. Knight , Jerrika Hinton , Jason George , Isaiah Washington , Kate Walsh , Martin Henderson , Brooke Smith , Jake Borelli , Greg Germann , Chris Carmack , Tessa Ferrer , Gaius Charles , Anthony Hill , Richard Flood .