Keesha returns from vacation to find that her prize cucumber has been stolen and was replaced with a smelly old pickle. When the evidence seems to point to Ms. Frizzle as the culprit, the class puts her on trial, with Keesha as prosecutor and Arnold as defense attorney. The Friz says a tiny group of troublemakers called the Mike Robe (microbe) Gang is responsible and takes the class for a visit into the teeny tiny world of microbes. There, they discover that even tiny living things can have a big effect.
Elenco: Daniel DeSanto , Stuart Stone , Erica Luttrell , Malcolm-Jamal Warner , Dan Tamberelli , Lily Tomlin , Frank Welker , Whoopi Goldberg , Susan Blu , Edward James Olmos , Andre Ottley-Lorant .