Christmas Eve in New York, and the lonely divorced publisher, Rose Collins, needs a miracle to improve the health of her mother, interned in a hospital with Alzheimers. She feels sorry for another patient and meets his visitor. Meanwhile, Nina Vasquez breaks her engagement with her beloved fiancé Mike due to his suffocating jealousy, but misses him. Mike is stalked by a stranger, bartender Artie Venzuela. The poor Jules arranges to spend Christmas Eve in the hospital, where he spent the best Christmas of his life when he was a teenager. The lives of some of these characters cross with others along the night.
Elenco: Susan Sarandon , Alan Arkin , Paul Walker , Penélope Cruz , John Doman , Maurizio Terrazzano , Robin Williams , Marcus Thomas , Sonny Marinelli , Daniel Sunjata , Chazz Palminteri , Rachelle Lefevre , Rob Daly , Billy Porter , Carmen Ejogo , Donna Hanover , Erika Rosenbaum , Merwin Mondesir , Una Kay , Sonia Benezra , Marcia Bennett , Howard Rosenstein , Jane Wheeler , David Julian Hirsh , Marguerite Kinh , Arthur Holden , Charles Rosenblum , Scott Faulconbridge , Budd Mishkin , Carmen Echeverria , Gianpaolo Venuta , Nicholas Haze , Ruth Chiang , Kevin Ryder , Andy Bradshaw , Robert Newton Brown , Bill Corday , Lindsay Owen Pierre , David Schaap , Lynne Adams , Kathleen Mackey , James Callaghan , Isabelle Champeau , Lucinda Davis , Anthony Ferriso , Loren Ferriso , Chantal Lonergan , Dante Palminteri , Adrianne Richards , Victoria Sanchez , Jennifer Seguin .