An exploration of the United States of America's war on drugs from multiple perspectives. For the new head of the Office of National Drug Control Policy, the war becomes personal when he discovers his well-educated daughter is abusing cocaine within their comfortable suburban home. In Mexico, a flawed, but noble policeman agrees to testify against a powerful general in league with a cartel, and in San Diego, a drug kingpin's sheltered trophy wife must learn her husband's ruthless business after he is arrested, endangering her luxurious lifestyle.
Elenco: Michael Douglas , Benicio del Toro , Jacob Vargas , Tomás Milián , Russell G. Jones , Michael O'Neill , Catherine Zeta-Jones , Dennis Quaid , Erika Christensen , Don Cheadle , Stacey Travis , Benjamin Bratt , Miguel Ferrer , Joel Torres , Beau Holden , Jeremy Fitzgerald , Mary Pat Gleason , Michael Saucedo , Tomás Milián , Jose Yenque , Emilio Rivera , Michael O'Neill , Jessica Yoshimura , Salma Hayek , Topher Grace , Albert Finney , Luis Guzmán , Viola Davis , Clifton Collins , Jr. .